In the first half of 2024, three prominent U.S. investors—Andreessen Horowitz, General Catalyst, and Khosla Ventures—emerged as the most active participants in Series A and B funding rounds globally. These firms led a total of seven or more early-stage investments, indicating a robust interest in nurturing new ventures.
Increased Investment Activity
Many of these active investors ramped up their investment pace compared to the previous year, suggesting a potential recovery in the venture capital market. Khosla Ventures, in particular, showed a significant increase in activity, leading Series B rounds for companies like Koloma, which focuses on geologic hydrogen services, and Waabi, an autonomous driving truck service co-led with Uber.
Key takeaways
- Andreessen Horowitz, General Catalyst and Khosla Ventures were the most active investors in global Series A and B rounds in the first half of 2024, each leading seven or more.
- By capital deployed, Arch Venture Partners led with $1.9 billion, including a co-led $1 billion round for AI drug discovery company Xaira Therapeutics.
- Healthcare and biotech took 40% of the 125 Series A and B investments tracked, with AI at 25%, financial services 13% and hardware 11%.
- The contrast with 2022 is stark: Tiger Global led or co-led 100 rounds in the first half of that year but only one in the same period of 2024.
- Insight Partners fell from 75 rounds to six over the same comparison.
Funding Amounts
When examining the amounts led in Series A and B rounds, Arch Venture Partners topped the list with $1.9 billion invested. This included a notable co-led funding of $1 billion in Xiara Therapeutics, an AI drug discovery company. General Catalyst also made headlines by leading rounds that reached $1 billion, including a significant investment in Mistral, an AI firm.
Sector Focus
The surge in funding during the first half of 2024 was primarily concentrated in two sectors: healthcare/biotech and AI. These industries accounted for 40% and 25% of the 125 Series A and B investments, respectively. Other sectors, such as financial services and hardware, also saw notable participation, representing 13% and 11% of investments.
Comparative Analysis
Looking back at the first half of 2022, the landscape was markedly different. Tiger Global led or co-led 100 rounds, while Insight Partners led 75. Fast forward to 2024, and Tiger Global’s activity has drastically decreased, leading only one round, while Insight Partners managed to lead six.
Market Outlook
The dynamic seed funding environment has raised questions about startups transitioning from seed to Series A funding. The uptick in Series A and B funding in early 2024, coupled with the increased activity from leading investors, signals a more optimistic outlook for the venture capital market moving forward.
Data Methodology
The information presented in this report is derived from reported data as of August 14, 2024. It is important to note that data lags are most pronounced at the earliest stages of venture activity, and all funding values are reported in U.S. dollars unless specified otherwise.
Frequently asked questions
What does the collapse in Tiger Global's activity indicate?
A structural change in who writes early-stage cheques. The crossover funds that dominated 2021 and early 2022 have largely withdrawn, leaving traditional venture firms to lead rounds again.
Which sectors are attracting early-stage capital?
Healthcare and biotech lead at 40% of tracked Series A and B deals, ahead of AI at 25%. That ordering is notable given how completely AI dominates later-stage headlines.
What did Khosla Ventures back?
It notably increased its pace, leading Series B rounds for Koloma in geologic hydrogen and for Waabi, an autonomous trucking company, co-led with Uber.








